10 November 2025
Monday
2-6pm SGT
The St. Regis Singapore
This symposium is a testament to the commitment of NUS Bia Echo Asia Centre for Reproductive Longevity and Equality (ACRLE) and CHA University Global IVF Group to advancing the science of Reproductive Medicine and to spearhead efforts in the research of human fertility to improve reproductive outcomes. The theme of this inaugural symposium is, ” Advances in Reproductive Medicine in Asia-Pacific” where experts in the field of Reproductive Medicine convene, present, and discuss the latest innovations and developments in assisted reproductive treatments and IVF technologies. This symposium is highly relevant to practitioners in Reproductive Medicine, clinical embryologists, Reproductive scientists and academics dedicated to this field.
Date:
Time:
Location:
10 November 2025
2 pm – 6 pm SGT
The St. Regis Singapore
Caroline’s Mansion (Annex building)
29 Tanglin Road
Singapore 247911
Date:
10 November 2025
Time:
2 pm – 6 pm SGT
Location:
St. Regis Singapore
Caroline’s Mansion (Annex building)
29 Tanglin Road
Singapore 247911
Dr Kwang Yul Cha
Chairman, CHA University Global IVF Group
Dr. Kwang Yul Cha is a globally recognized thought leader in reproductive medicine and the Chairman of CHA University Global IVF Group.
As a clinician and research scientist, Dr. Cha achieved the world’s first in-vitro maturation (IVM) of human oocytes (1989), developed a method for oocyte cryopreservation using vitrification (1998) and established the world’s first oocyte bank (1999), amongst other important milestones. His pioneering achievements have been featured numerously in various publications including TIME magazine and cited in major O&G textbooks including Novak’s. Dr. Cha has over 200 peer-reviewed publications to date and leading academic societies including ASRM, KSRM and KSSCR have each established prestigious awards bearing his name in recognition of lasting contributions to the field. Dr. Cha co-founded the Pacific Society for Reproductive Medicine (PSRM), formerly served as a visiting professor at Columbia University and received his medical education from Yonsei University.
Professor Chong Yap Seng
Lien Ying Chow Professor in Medicine
Dean, National University of Singapore Yong Loo Lin School of Medicine
Deputy Chief Executive (Education & Research), National University Health System
Professor Chong Yap Seng is the Dean of NUS Medicine, one of the leading medical schools in Asia. Since he assumed the role of Dean in 2019, NUS Medicine has risen to rank 17th on the 2025 Times Higher Education World University rankings and 18th on the 2025 QS World University Rankings for Medicine.
In his appointed role as Deputy Chief Executive (Education and Research) of the National University Health System (NUHS), Professor Chong advances NUHS’ academic mission through his oversight of the academic and research development at all NUHS institutions.
Formerly the Executive Director (2015-2021), Professor Chong now oversees clinical programmes that seek to promote health and human capacity in Singapore and the world as the Chief Clinical Officer at the Institute for Human Development and Potential, Agency for Science, Technology and Research (A*STAR). These programmes include the Growing Up in Singapore Towards healthy Outcomes (GUSTO) and the Singapore Preconception Study of long-Term maternal and child Outcomes (S-PRESTO) longitudinal studies that examine how conditions in pregnancy and early childhood influence the health and development of women and children.
Professor Ho Sup Yoon
Executive Vice President (Research)
CHA University, Korea
Prof Yoon is the Executive Vice President (Research) and Professor in the College of Pharmacy, CHA University, Korea. As Executive Vice President (Research), he spearheads the university’s research strategy, promotes multidisciplinary initiatives, and drives research translation to address unmet medical needs. He has also served as President of the CHA Advanced Research Institute and is currently an Advisor to the CHA R&D Institute at CHA University Bundang Medical Center.
Prof Yoon earned his BSc from Seoul National University, MSc from KAIST, and PhD from the University of Chicago. Previously, he was a founding faculty member of the School of Biological Sciences at Nanyang Technological University Singapore, where he also served as Research Director (Biomedical Sciences) in the President’s Office, shaping the university’s biomedical research vision and strategy. His research focuses on developing novel therapeutics in neurodegenerative disorders and cancer. Prof. Yoon is a recipient of the Abbott Drug Discovery Impact Award and the Overseas Korean Scientist of the Year Award.
Dr. Huang Zhongwei
Deputy Director, Adjunct Assistant Professor, NUS Bia-Echo ACRLE
Adjunct Assistant Professor Zhongwei Huang is Deputy Director of NUS Bia-Echo Asia Centre for Reproductive Longevity & Equality, Yong Loo Lin School of Medicine, National University of Singapore. He concurrently serves as a Consultant at the Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynaecology, National University Hospital, Singapore. Adjunct Assistant Prof Huang’s subspecialties include reproductive endocrinology & infertility and sexual medicine, and he is accredited by the Ministry of Health (Singapore) as an assisted reproductive techniques (ART) specialist. Dr Huang completed his PhD on ovarian biology in 2011 at the University of Oxford, United Kingdom, and continues to contribute to the field as a clinician-scientist. His current research focuses on discovering innovative solutions through basic and translational research to change women’s life narrative of reproductive inevitability to reproductive longevity. Dr Huang’s research has been published in renowned journals such as Cell Research, Nature Aging, Nature Communications, AJOG, BJOG, Human Reproduction, Fertility & Sterility, Molecular Human Reproduction and Reproductive Sciences.
Professor Majid Warkiani
Professor, School of Biomedical Engineering, University of Technology Sydney
Dr Warkiani is a Professor and CINSW Fellow in the School of Biomedical Engineering, University of Technology Sydney (UTS), Australia. He received his PhD in Bioengineering from Nanyang Technological University (NTU, Singapore), and undertook postdoctoral training at Massachusetts Institute of Technology (MIT, USA). Dr. Warkiani is the co-director of the Institute for Biomedical Materials & Devices (IBMD) at UTS and the co-founder of two startups, NeoGenix Biosciences (https://www.neogenixbiosciences.com/) and SMART MCs (https://smartmcs.com.au/). Dr Warkiani’s research focuses on developing innovative cell biology solutions through microfluidics and organoid-on-a-chip systems. His team has pioneered advanced cell sorting technologies for stem cells, exosomes, circulating tumor cells, and fetal cells, enhancing diagnostic precision and advancing regenerative therapies. In organoid-on-a-chip technology, he designs sophisticated 3D platforms that replicate tissue functions, such as human skin, offering valuable insights into disease modeming and drug discovery with stem cell-derived exosomes.
Group webpage: www.warkianilab.com
Associate Professor Ok Hee Jeon
Department of Convergence Medicine, Korea University College of Medicine, Seoul, South Korea
Dr. Ok Hee Jeon earned her Ph.D. in Biomedical Engineering from Johns Hopkins University in 2017, where her pioneering research on cellular senescence elucidated its role in musculoskeletal degeneration following injury and aging (Jeon et al., Nature Medicine, 2017). As a postdoctoral fellow at the Buck Institute for Research on Aging, she uncovered senescence propagation and circulating pro-aging factors as key mechanisms driving systemic aging (Jeon et al., Nature Metabolism, 2022). Currently, an Associate Professor at Korea University College of Medicine, her research spans from aging biology to engineering-based solutions, as she investigates novel aging mechanisms and develops regenerative and pharmacologic therapies by integrating MPS, biomaterials, and others to target senescent cells. Her recent research extends to reproductive medicine, where she identifies cellular senescence-associated biomarkers linked to women’s fertility and ovarian reserve (Environmental Research, 2024; Menopause, 2023; Rejuvenation Research, 2022), contributing to improved diagnostic and therapeutic strategies in reproductive aging.
Associate Professor Ji Hyang Kim
Department of Obstetrics and Gynecology
Center Director, Fertility Center of CHA Bundang Medical Center, CHA University School of Medicine
Chairman, Cha Biotech Reproductive Medicine Research Laboratory
Professor Ji Hyang Kim is an associate professor and center director at the Fertility Center of CHA Bundang Medical Center and CHA University School of Medicine. She also serves as chairman of the CHA Biotech Reproductive Medicine Research Laboratory. She has researched and published numerous articles on assisted reproductive technology, reproductive function regeneration, and genomic studies of reproductive diseases. Her primary research interests include ovarian rejuvenation and endometrial regeneration in intractable infertility. Recently, she implemented a clinical application of platelet-rich plasma for refractory thin endometrium, poor ovarian reserve (POR), and premature ovarian insufficiency (POI), obtaining Korean government approval for its clinical use. Additionally, she is conducting government-funded research on cell therapeutic agents for POI/POR and developing artificial intelligence-based digital solutions for ART, such as gamete and embryo selection and a clinical decision support system. She actively participates in various academic societies for reproductive endocrinology and infertility as a council member.
Professor Jean Kyung-Ah Lee
Department of Biomedical Science, College of Life Sciences, CHA University
Executive Director, CHA University Global IVF Group
Upon finishing her doctoral training at the University of Illinois at Urbana-Champaign, she joined the CHA University Fertility Center in Seoul, Korea, in 1992. She served as the Dean of the College of Life Science, CHA University, as the Vice President of the KSRM, and has been serving as an associate editor of the Clinical and Experimental Reproductive Medicine (CERM), the official journal of the PSRM for a decade. She has served as the Executive Director of CHA University Global IVF Group for the past 8 years.
She has dedicated her research to reproductive medicine for the last 30 years with a special focus on ovarian physiology and has published over 150 peer-reviewed journals, book chapters and conference proceedings. Her current research projects are focused on studying the molecular regulation of oocyte’s cytoplasmic maturation as well as the reinforcement of ovarian function by using stem cells in advanced age.
Professor Jerry Chan Kok Yen
SingHealth Duke-NUS Medical School,
KKIVF Centre, KK Women’s and Children’s Hospital, Singapore
Prof. Jerry Chan is a Senior Clinician-Scientist Obstetrician and Gynaecologist (OBGYN) with research interests in fetal immunology and molecular therapy, reproductive medicine and life-course epidemiology. His research straddles several fields of cutting-edge science underpinning advances in reproductive biology, from early fetal development and immunology, to fetal therapy and perinatal advancements through optimising fertility and perinatal outcome; and seeks to translate discoveries from the laboratory and clinical arena into clinical applications to improve patient outcomes. He has published over 300 papers including in prestigious journals such as the The Lancet, Nature, Nature Medicine, Science and Cell; and is a Highly Cited Researcher (ClarivateTM).
Dr. Liow Swee Lian
Scientific Director,Virtus Fertility Centre Singapore
Dr. Liow is a certified Clinical Embryologist. He has vast research experience and is one of the pioneers in micromanipulation techniques like ICSI, IMSI, Polarized Light Microscopy (Oosight) and, laser micromanipulation techniques. He has his professional training in Human ES Cell Culture Methods (Wicell Research Institute, USA), PGD (University College London, United Kingdom), laser micromanipulation (University of Heidelberg, Germany).
Dr. Liow is also the author and co-author of many research papers published in peer – review international journals and books.
His research interests include embryo culture system, Preimplantation Genetic Testing (PGT), ovarian tissue cryopreservation, vitrification of oocytes and embryos, male infertility, sperm DNA fragmentation, fertility preservation, stem cell biology. He is regularly invited to speak in various scientific congresses and workshops. He is currently an Associate Editor for Fertility and Reproduction, Co-Chair for the ASPIRE Embryology Special Interest Group (SIG) and involved in establishing the ASPIRE ART Guidelines and ASPIRE Embryology Certification Course. He also holds membership in ESHRE, ASRM,PGDIS and ISFP.
2:30 – 2:35 pm
Opening Remarks
Professor Yoon Ho Sup, Executive Vice President (Research) & Professor, College of Pharmacy, CHA University
Dr. Huang Zhongwei, Deputy Director, Adjunct Assistant Professor, NUS Bia-Echo ACRLE
2:35 – 2:40 pm
Welcome Address
Dr. Kwang Yul Cha, Chairman, CHA University Global IVF Group
2:40 – 2:45 pm
Congratulatory Address
Professor Chong Yap Seng, Lien Ying Chow Professor in Medicine, Dean, NUS Yong Loo Lin School of Medicine
2:45 – 2:55 pm
Fertility Landscape in Asia – Pacific
Chris Chung, CHA Asia-Pacific
2:55 – 3:15 pm
Microfluidic and AI-Driven platforms for Next-Generation assisted reproduction
Professor Majid Warkiani, School of Biomedical Engineering, University of Technology Sydney
3:15 – 3:35 pm
Cellular Senescence in ovarian ageing
Associate Professor Ok Hee Jeon, Department of Convergence Medicine & Biomedical Sciences Korea University College of Medicine
3:35 – 3:55 pm
AI-Driven 3D Imaging: Looking Beyond the Visible in Embryo Selection
Associate Professor Ji Hyang Kim, Department of Obstetrics and Gynecology, CHA Bundang Medical and Fertility Center, CHA Women’s Hospital
3:55 – 4:15 pm
A novel artificial endometrium model of embryo implantation in vitro,
Professor Jean Kyung-Ah Lee, Department of Biomedical Science, College of Life Sciences, CHA University, Executive Director, CHA University Fertility Center
4:15 – 4:40 pm
Tea Break / Networking
4:40 – 5:00 pm
TBA
Dr. Melissa Durgahshree Tharmalingam, Principal Embryologist, KKIVF Centre, KK Women’s and Children’s Hospital, Singapore
5:00 – 5:20 pm
IVF Laboratory Automation
Professor Jerry Chan Kok Yen, SingHealth Duke-NUS Medical School, KKIVF Centre, KK Women’s and Children’s Hospital, Singapore
5:20 – 5:40 pm
Sperm selection to optimize ART success
Dr. Liow Swee Lian, Scientific Director, Virtus Fertility Centre, Singapore
5:40 – 5:45 pm
Closing Remarks
6:00 – 8:30 pm
Dinner – Invited
The work of the Centre is focused within four strategic tracks. The effort within the tracks will seek to find ways to improve and lengthen female reproductive health and longevity, help women to preserve and improve their reproductive systems for conception and general health, potentially enable women to conceive safely in their later years, and to remain healthy longer. ACRLE advocates and educates on reproductive equality for all and works closely with other academic institutions and stakeholders to change the narrative of reproductive longevity and equality.
CHA University Global IVF Group (CHA) is one of Asia-Pacific’s leading and most comprehensive fertility care networks, with more than 50K cycles per annum and internationally recognized for clinical & scientific excellence in reproductive medicine. With over four decades of experience, CHA has become a global leader in advanced IVF technologies with outstanding pregnancy outcomes, patient-centered care, and pioneering academic research.
Building on a rich legacy of innovation, CHA has been at the forefront of IVF scientific discoveries and has pioneered “world firsts” in treatment protocols such as the development of an oocyte cryopreservation technique using slush nitrogen in 2005. Since its first successful IVF pregnancy in 1989, CHA teams have been honored with 14 academic awards from international organizations such as ASRM, ESHRE and PSRM.
As Korea’s clear authority in fertility treatment and the nation’s leading brand in women’s health, CHA is also regarded as one of the world’s premier institutes for IVF patient care. Its Korea-based network comprises seven major world-class centers serving patients from more than 30 countries. Internationally, the broader CHA Group encompasses a global system across seven countries throughout the Pacific Rim including Korea, Australia, the United States, Japan, Singapore, Vietnam, and Indonesia, and provides world-leading efficacy and patient experience across general hospital, women’s, specialized and fertility care spectrums.
Research Assistant
Abraham is a research assistant under the Bia-Echo Asia Centre for Reproductive Longevity and Equality (ACRLE). He graduated with a Bachelor in Engineering (Biomedical Engineering) at the National University of Singapore. With experiences in different labs, he hopes to further elucidate the understanding of reproductive health and longevity through various models and mechanisms.
Research Assistant
Hui Wen is a Clinical Research Coordinator with a BSc in Biomedical Science from La Trobe University and a background as a Medical Laboratory Technologist. Skilled in laboratory diagnostics, regulatory compliance, and patient care, she brings analytical expertise and attention to detail to the O&G research setting, supporting clinical studies that advance women’s health while ensuring data integrity and ethical research practices.
Research Associate
Devi is a Research Associate under the Bia-Echo Asia Centre for Reproductive Longevity and Equality (ACRLE). She received her BSc in Biotechnology from the Hong Kong University of Science and Technology (HKUST) and MSc in Clinical Embryology from Oxford University. She has a license from the Singapore Ministry of Health (MOH) to practice embryology and has previous experience as a Clinical Embryologist. She is dedicated in pursuing research in fertility preservation and reproductive longevity for women of various ages.
Research Assistant
Xue Ting is research assistant under the Bia-Echo Asia Centre for Reproductive Longevity and Equality (ACRLE). She graduated with a first-class honors degree in Biomedical Sciences at Northumbria University in 2020. She has one published manuscript as the first author in her final year of university. She is experienced in animal handling, and has past experiences with veterinary care and rehabilitation.
Adjunct Senior Research Fellow
Dr Chervin Lam leads the Health Communication Team at ACRLE, exploring communication issues surrounding reproductive health information. Currently, there are many questions that are left unexplored in the literature. For example, where do women go to for reproductive health information? What obstacles do they face? How can we improve reproductive health education? Together with scholars from Shanghai Jiaotong University, Lam and his team are pioneering research in this novel and exciting intersection between social science and reproductive health.
Lam has published in several premier journals in the field, such as Health Communication and Journal of Health Communication. He is co-author of a book, Health Advocacy: A Communication Approach, which is read for a graduate class at Purdue University, USA.
Research Assistant
Ms. Shaili P Sashidharan graduated with a Bachelor of Sciences in Biomedicine (Hons). She is currently working as a research assistant under Dr Huang Zhongwei. Her mainstream projects are mostly fertility related, focusing more on the men’s health. She has 14 years of experience in the research field and has assisted on many other projects as well.
Research Assistant
Jovin is a research assistant under the Bia-Echo Asia Centre for Reproductive Longevity and Equality (ACRLE). She shows dedicated interest in the field of healthcare and is zealous to be part of the forefront in steering the development of women health. She is also earnest to pursue personal growth for her endeavours towards enriching the healthcare network. In her spare time, she loves to play with her pets.
Research Associate (Biostatistics)
Ms. Yang graduated with a Master of Public Health (MPH) degree in Biostatistics from Oregon Health and Science University. She possesses extensive experience in analyzing clinical data from both retrospective and prospective studies. She joined ACRLE to further explore and contribute to the field of women’s reproductive health research.
Senior Research Fellow
Gong Min obtained her Bachelor of Clinical Medicine from Tongji Medical College, and her PhD from Yong Loo Lin School of Medicine – NUS. Gong Min’s research focuses on using multi-omics data analysis to investigate the emerging role of genetic alterations and epigenetic modulations associated with women’s and children’s health (e.g., preterm birth, gestational diabetes mellitus, and reproductive longevity). She is also co-leading multiple projects related to Paternal Origins of Health and Disease (POHaD) to unravel the underlaying mechanism of transgenerational epigenetic inheritance.
Senior Research Fellow
Dr. Benny is a Senior Research Fellow at the National University Hospital, Department of Obstetrics and Gynecology. She obtained her PhD from NUS and completed her postdoctoral training in the USA. Her research focus is on multi-omics strategies and translational clinical research for the enhancement of women’s health and reproductive longevity. She is also interested in promoting preconception health, developing novel biomarkers for PCOS as well as unraveling the unique (epi)genetics associated with Asian ethnicities. Dr. Benny has extensive experience in maternal-fetal medicine, big data integration, biomarker discovery and personalized medicine.
Research Assistant
Ms Lau graduated with a BSc (Hons) in Pharmacology-Biochemistry from the University of Leeds, UK and a MSc from the National University of Singapore. She joins Ovarian Biology and Senescence Study in ACRLE under Asst Prof Huang. She has experience in Reproductive Pharmacology & Sexual Medicine Lab. She is interested in therapeutics, pathophysiology, sexual function/dysfunction, and reproductive health.
Research Fellow
Dr. Vani Khare is a scientist and a humanitarian. She has joined ACRLE as a postdoctoral fellow, where her research focus is on female reproductive longevity, perimenopause, and menopause healthcare. She is also a staunch advocate for women’s reproductive and health care rights. Before joining ACRLE, she worked as a postdoctoral fellow at A*STAR Singapore and held a senior scientist role in a pharma company. Additionally, she founded and led non-profit initiatives in India and Singapore, working to safeguard the rights of children and combat child sexual abuse.
Senior Research Fellow
Huili Guo graduated from the University of Cambridge in 2005 with a B.A. degree in Natural Sciences. In 2011, she received the Ph.D. degree in Biology from the Massachusetts Institute of Technology. She performed her thesis research in the laboratory of Prof. David Bartel at the Whitehead Institute for Biomedical Research, where she used ribosome profiling and RNA-Seq to study the molecular consequences of microRNA-mediated repression in mammalian systems. This work was published in Nature in 2010. This highly-cited piece of work is recommended by the Faculty of 1000, which identifies the most significant articles in biomedical research publications. Huili is a recipient of National Science Scholarships from the Agency for Science, Technology and Research (A*STAR) in 2002 (BS) and 2006 (PhD). She was an Adjunct Assistant Professor with the Department of Biological Sciences, National University of Singapore. Huili was also an Ambassador for the STEM (Science, Technology, Engineering and Mathematics) programme run by the Singapore Committee for UN Women. She is a recipient of the L’Oréal Singapore For Women In Science National Fellowship (2014) and the Young Scientist Award (2016). Huili was an Independent Fellow at IMCB from 2012-2021.
Assistant Manager
Eunice manages the wet laboratory in Bia-Echo Asia Centre of Reproductive Longevity and Equality (ACRLE), located in Centre of Life Science. She also works closely with the Deputy Director and Centre lead in administration and operations.
Senior Manager
Dione is the Research Centre Administration Lead at Bia-Echo Asia Centre for Reproductive Longevity and Equality (ACRLE). With more than 15 years of experience in the education sector, Dione Ng has held multiple administrative portfolios in NUS, SMU and MOE. Dione works closely with the Deputy Director in managing the Centre’s research grants, day-to-day corporate administration and operations.
Principle Investigator
Professor Dean Ho is currently Provost’s Chair Professor, Director of The Institute for Digital Medicine (WisDM) at the Yong Loo Lin School of Medicine, Director of the N.1 Institute for Health (N.1), and Head of the Department of Biomedical Engineering at the National University of Singapore.
Prof. Ho and collaborators successfully developed and validated CURATE.AI, a powerful digital medicine platform that has optimized human treatment for broad indications ranging from oncology to infectious diseases. He co-led the first inhuman clinical trials that have resulted in completely halted disease progression and durable patient responses that substantially outperformed standard of care approaches.
Principal Investigator
Prof Rong Li served as the Director of the Center for Cell Dynamics in the Johns Hopkins School of Medicine. She has had over 25 years of independent research on cellular dynamics and mechanics employing interdisciplinary approaches. She was recruited to NUS in 2019 as the second Director of MechanobioIogy Institute (MBI).
Her research areas include Cellular dynamics and mechanics, cell and tissue aging and regeneration, and chromosomal biology in cellular adaptation. The diverse projects in Prof Rong Li’s lab contribute to two main research thrusts: cell and tissue aging; cellular and organismal adaptation. The study on aging focuses on understanding dynamic changes of crucial cellular components during the aging process and how these changes alter the mechanical functions of cells and tissues. The insights gained will be applied to the development of new methods for prolonging healthy aging and the repair and regeneration of deteriorated functions. The study of adaptation aims to understand the dynamics of genetic and epigenetic determinants of cells and tissues under acute or chronic stress which lead to adaptive behaviors ultimately beneficial or detrimental to the fitness of the organism. A potential application of the discoveries in this area is the prevention of cancer associated with chronic inflammatory diseases.
Principle Investigator
Prof. Zhang is a clinical epidemiologist and an expert in women’s health research. Prof. Zhang’s work unites biochemistry, genetics, nutrition, clinical medicine, and public health. It is at the interface of disease etiology and prevention strategies in women’s and children’s health over the lifespan and across generations. She is leading a multi-disciplinary program focusing on the improvement of women’s health through dietary and lifestyle modifications, omics research, and early screening in general.
Deputy Director
Zhongwei is a clinician-scientist and MOH accredited assisted reproductive techniques (ART) specialist who focuses on managing couples with fertility issues. He completed his PhD in 2011 under Associate Professor Dagan Wells at University of Oxford on effects of reproductive ageing via understanding the mechanisms of human oocyte aneuploidy and utilizing human cumulus cells as a non-invasive biomarker of oocyte quality.
Director
Prof Brian Kennedy is internationally recognised for his research in the basic biology of ageing and as a visionary committed to translating research discoveries into new ways of delaying, detecting, preventing and treating human ageing and associated diseases. He is the Director of the NUHS Centre for Healthy Longevity. He also serves as a Distinguished Professor in Biochemistry and Physiology Yong Loo Lin School of Medicine at National University Singapore. The Centre seeks to demonstrate that ageing interventions can be successfully employed in humans to extend healthspan, the disease-free and highly functional period of life.